A Clinical Update: Post-Traumatic Stress

 

                                                                 By Edward G. Morhauser, M.D. 


 

 

Sometime ago a new patient—I’ll call her Sally—visited my office complaining of persistent panic attacks. She was obsessed with the idea that she was going to die imminently. This feeling apparently resulted from a recent severe sinus infection from which Sally had fully recovered. But instead of being relieved by her complete recovery, she was terrified of dying.

At first I was puzzled by Sally’s overreaction to this illness, so I asked her what she thought was causing her concern. She told me she couldn’t imagine what the problem was because there was nothing wrong with her.

Slowly Sally began to tell me the story of her life. She confided that for several years as a child she and her family had been trapped in a war zone. As traumatic as this experience was, Sally had lived a pleasant and fulfilling life as a professional woman, wife, and mother. Then, without warning, her father, with whom she was very close, died in her arms. A few months later, her husband suffered a sudden fatal heart attack. The next year her brother committed suicide, and the most painful of all, her son was killed in an accident. In another few months, her mother died as well. Five members of her immediate family died within a six-year period. But it was the sinus infection that brought all the trauma of those last few years to the surface and caused Sally to face her own mortality. Sally was exhibiting the symptoms of classic Post Traumatic Stress Disorder.

I first became aware of this condition in soldiers flown directly to our U.S. Navy hospital in Boston from the combat zone in Vietnam. Then we called their symptoms “shell shock” and “battle fatigue,” but we didn’t really know what we were dealing with.

Post-traumatic stress disorder (PTSD) is a condition that can develop in anyone who experiences, or merely witnesses, a traumatic incident or series of incidents where they feel their safety is threatened. Not everyone reacts to these incidents in the same way. Not all PTSD occurs immediately after the causal incident, but may be triggered even years later. Most people who suffer a traumatic incident will experience symptoms immediately afterward but soon will go on with their lives. Predisposed persons, with higher levels of anxiety, make the trauma the focus of their lives. When this focus moves from the trauma itself to the physical disabilities caused by their reactions to the trauma—chronic anxiety, insomnia, depression, sometimes substance abuse, unemployment—the patient is said to be suffering from chronic PTSD. One study showed that the rate of full remission of chronic PTSD was only 18 percent (Zlotnick et al. 1999). It is estimated that currently 5 percent of the population of the United States has PTSD and 8 percent has had PTSD at some point in their lives; occurrence is consistently higher among women.

The tragedy of September 11, 2001, brought PTSD into the public spotlight and created new opportunities to study this disabling condition. Recent research has shown that if therapy can be started within 24 hours of the incident, the condition can sometimes be lessened or even blocked.

 

A Specific Disorder

PTSD describes a specific disorder. It can become a chronic psychiatric disorder and can persist for decades or sometimes for life. It is estimated that the economic burden of PTSD in the United States is $3 billion a year. Symptoms most often begin within three months after the event and can occur in clusters including

  1.  Intrusive, recurring recollections and nightmares: sufferers repeatedly re-live their ordeal. Also, if they witness a similar incident, a filmed replay showing the incident, or are reminded of the ordeal on an anniversary, etc., their experience may be reactivated and symptoms can be as severe as before.

  2.  Avoidance: sufferers may try to avoid any situation that might remind them of the event, causing feelings of detachment, isolation from their personal support group, and loss of interest in activities previously enjoyed.

  3.  Numbing: symptoms are typically experienced as a loss of emotions, particularly positive feelings.

  4.  Hyperarousal: insomnia, irritability, anger, difficulty relating to others, difficulty concentrating, drug abuse; possible physical symptoms might include increased blood pressure and heart rate, rapid beating, muscle tension, nausea, and diarrhea.

  Certain individuals are predisposed to developing PTSD. A history of such conditions as trauma, depression, anxiety disorders, financial reversals, divorce, comorbid disorders, and disrupted parental attachments are risk factors that can contribute to the onset of PTSD. High rates of comorbidity complicate treatment decisions of PTSD patients concerning whether to treat the disorders concurrently or sequentially.

For those PTSD patients who are mildly to moderately affected, group therapy has been perhaps the most helpful. Patients can discuss traumatic memories, symptoms, and functional deficits with others who have been affected similarly.

 

More severe cases may need multiple therapies including the following:

PSYCHOPHARMACOLOGY:

  Selective serotonin reuptake inhibitors (SSRI):  Prozac, Zoloft, Paxil

  Tricyclic antidepressants

  Benzodiazepines

  Anticonvulsants

  Antipsychotics

  Adrenergic inhibitors

 

Where early intervention is possible, within hours after the trauma—

  adrenaline blocking agent (propranolol) based on an adrenaline model of prolonged terror.

  debriefing, which is controversial because of possible adverse effects.

Medication is helpful in easing associated symptoms of depression and anxiety and aids sleep. Drug therapy appears to be highly effective for some individuals and is helpful for many more.

 

PSYCHOTHERAPY:

Cognitive-behavioral therapy (CBT): working with cognition to change emotions, thought patterns, and behaviors.

  learning to cope with anxiety,

  managing anger,

  preparing for stress reactions,

  handling future trauma symptoms,

  addressing urges to use alcohol or drugs,

  communicating and relating effectively with people, social skills, marital therapy.

 

Exposure therapy: a type of cognitive-behavioral therapy, which uses repeated, detailed imagining of the trauma (exposure) in a safe, controlled context to help the survivor face and gain control of the fear and distress that was overwhelming during the trauma.

 

Eye Movement Desensitization and Reprocessing (EMDR): a relatively new treatment for traumatic memories that involves elements of exposure therapy and cognitive-behavioral therapy. Although research in this form of treatment is still evolving, some evidence indicates that the therapeutic element unique to EMDR, attentional alternation, may facilitate the accessing and processing of traumatic material.

 

Psychodynamic Psychotherapy: focus on the emotional conflicts caused by the traumatic event, particularly as they relate to early life experiences. Through the retelling of the traumatic event to a calm, empathic, compassionate, and nonjudgmental therapist, the patient achieves a greater sense of self-esteem, develops effective ways of thinking and coping, and learns to deal more successfully with intense emotions. The therapist helps the survivor identify current life situations that set off traumatic memories and worsen PTSD symptoms. 

 

EDUCATION AND SUPPORTIVE MEASURES:

Informing patient about the expected responses to trauma,

strategies for decreasing exposure to traumatic event,

stress-reduction techniques,

emphasizing the importance of self-care and mental activity, and early referral if symptoms persist.

PTSD is not a new illness, but the therapies and medications for treating it are continuing to evolve and improve. 

 

Dr. Morhauser is a psychiatrist in San Mateo.

 

References:

The Expert Consensus Guideline Series: Treatment of Post-traumatic Stress Disorder, J Clin Psychiatry 1999; 60 (suppl 16). Foa EB, Davidson JRT, Frances A, eds. Department of Veterans Affairs; National Center for Post-traumatic Stress Disorder.

Posttraumatic Stress Disorder, Grand Rounds Case Conference, Morhauser, EG.